« Back
Home /
Recombinant human DPP4/CD26 protein

Recombinant human DPP4/CD26 protein

€1,066.00

Excl. VAT

Item no.	NKM-DPP0901-500ug
Manufacturer	NKMAX
Amount	500ug
Category	Oncology Metabolism Diabetes By Cell Type Peptides & Proteins Recombinant Proteins SDS-PAGE
Type	Proteins Recombinant
Applications	SDS-PAGE
Specific against	other
Conjugate/Tag	His-Tag
Purity	> 95% by SDS-PAGE
NCBI	NP_001926
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	DPP4, CD26, Dipeptidyl peptidase-4, DPPIV, ADABP, ADCP2, TP103, Dipeptidyl peptidase-4, DPP4, dipeptidyl-peptidase 4, CD26, dipeptidylpeptidase IV (CD26 adenosine deaminase complexing protein 2), adenosine deaminase complexing protein 2,
Available
Antigen Species	Human
Bioactivity Comment Only	Specific activity is > 200unit/mg, One unit produces 1.0 umole of p-Nitroaniline from Gly-Pro- p-Nitroaniline per minute at pH 8.0 at 37C.
Concentration	0.5mg/ml (determined by absorbance at 280nm)
Description	DPP4, dipeptidyl peptidase-4 is a complex enzyme expressed on the surface of most cell types and is a serine exopeptidase that cleaves x-proline dipeptides from the N-terminus of polypeptides. DPP4 protein is associated with intracellular signal transduction, apoptosis and plays an important role in tumor biology. There are at least 63 substrates which can bind specifically to DPP4 enzyme including growth factors, chemokines, neuro peptides. Furthermore, DPP4 plays a major role in glucose metabolism by cleaving incretins such as glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). Recombinant human DPP4 protein was expressed with c-terminal His-tag in high-5 cells using baculovirus expression system and purified by using conventional chromatography techniques.
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Expression System	Baculovirus
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 1mM EDTA, 10% glycerol
Gene Category	Enzymes & Proteases
General References	Pratley RE and Salsali A. (2007) Curr Med Res Opin. 23(4):919-31; ; Rosenstock J. and Zinman B. (2007) Curr Opin Endocrino Diabetes Obes.60(11):1454-70; ; Barnett A. (2006). J.Clin. Pract. 60(11):1454-70; ;
Molecular Weight	85.4 kDa (737aa) confirmed by MALDI-TOF
Storage	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 500ug

Listprice: €1,066.00

Price: €1,066.00

available

Delivery expected until 8/28/2025

Quantity:

Compare