Comparison

Recombinant human TIM-3 protein

€1,066.00
Excl. VAT
Item no. NKM-ATGP3381-250ug
Manufacturer NKMAX
Amount 250ug
Category
Type Proteins Recombinant
Specific against other
Conjugate/Tag hIgG-His-Tag
Purity > 85% by SDS - PAGE.
Sequence ADLSEVEYRA EVGQNAYLPC FYTPAAPGNL VPVCWGKGAC PVFECGNVVL RTDERDVNYW TSRYWLNGDF RKGDVSLTIE NVTLADSGIY CCRIQIPGIM NDEKFNLKLV IKPAKVTPAP TRQRDFTAAF PRMLTTRGHG PAETQTLGSL PDINLTQIST LANELRDSRL ANDLRDSGAT IRIGLEPKSC DKTHTCPPCP APELLGGPSV FLFPPKPKDT LMISRTPEVT CV
NCBI NP_116171
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Hepatitis A virus cellular receptor 2, HAVCR2, HAVcr-2, KIM-3, Tim-3, TIM3, TIMD-3, TIMD3, FLJ14428, HAVcr-2, Havcr2, HAVR2_HUMAN, Hepatitis A virus cellular receptor 2, Kidney injury molecule 3, KIM 3, KIM3, T cell immunoglobulin and mucin domain containing 3, T cell immunoglobulin mucin 3, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin family member 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, Tim 3, TIM-3, TIM3, TIMD-3, TIMD3
Available
Antigen Species
Human
Applications info
SDS-PAGE
Concentration
0.5mg/ml (determined by Absorbance at 280nm)
Description
HAVCR2, also known as hepatitis A virus cellular receptor 2, is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not on Th2 cells. It was the first surface molecule that specificallyidentifies Th1 cells in both mice and human. It interactions with Galectin-9 can alternatively trigger immune stimulatory effects, such as the coactivation of NK cell cytotoxicity. Recombinant human HAVCR2, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Domain
22-202aa
Endotoxin
< 1.0 EU per 1ug of protein (determined by LAL method)
Expression System
Baculovirus
Formulation
Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol
Gene Category
Immunology, Virus
General References
Geng H., et al. (2006) J Immunol. 176:1411-1420.
Anderson AC., et al. (2006) Curr Opin Immunol. 18:665-669.
Molecular Weight
47.3kDa (423aa)
40-57kDa (SDS-PAGE under reducing conditions)
Storage
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 250ug
Available: In stock
Listprice: €1,066.00
Price: €1,066.00
available

Delivery expected until 9/25/2025 

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