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Human IL-17A / CTLA-8 Protein, Tag Free (MALS verified)

Human IL-17A / CTLA-8 Protein, Tag Free (MALS verified)

€2,645.00

Excl. VAT

Item no.	ILA-H5219-1mg
Manufacturer	ACROBiosystems
Amount	1mg
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Powder
Specific against	Human (Homo sapiens)
Conjugate/Tag	Unconjugated
Purity	>90% as determined by SDS-PAGE.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IL-17A,Interleukin-17A,CTLA-8,IL-17
Available
Bioactivity Legend 1	Immobilized Human IL17A, Tag Free (Cat. No. ILA-H5219) at 0.5 μg/mL (100 μL/well) can bind Human IL-17 RA, His Tag (Cat. No. ILA-H5222) with a linear range of 8-125 ng/mL (QC tested).
Buffer	PBS, pH7.4
Characteristics	This protein carries no "tag". The protein has a calculated MW of 15.1 kDa. As a result of glycosylation, the protein migrates as 16 kDa, 17 kDa and 19 kDa under reducing (R) condition, and 27-34 kDa under non-reducing (NR) condition (SDS-PAGE).
Description	Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8), which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also, IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore, IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Endotoxin Level	Less than 1.0 EU per μg by the LAL method.
Exp Region	Gly 24 - Ala 155
Expression System	HEK293
Molecular Weight	15.1 kDa
Molecule	IL-17A
SDS-PAGE Legend	Human IL17A, Tag Free on SDS-PAGE under reducing (R) and non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Shipping condition	RT
Storage	-20℃

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1mg

Listprice: €2,645.00

Price: €2,645.00

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Delivery expected until 8/28/2025

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