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IL-17A-17F Heterodimer Protein, Mouse (Biotinyllated, HEK293, His-Avi) European Partner

€1,087.00
Excl. VAT
Item no. HY-P77708-100ug
Manufacturer MedChem Express
Amount 100 ug
Category
Type Proteins Recombinant
Specific against other
Purity 95.0
Citations [1]Chen K, et al. Interluekin-17A (IL17A). Gene. 2017 May 30;614:8-14.
[2]Chang SH, et al. IL-17F: regulation, signaling and function in inflammation. Cytokine. 2009 Apr;46(1):7-11.
[3]Iwakura Y, et al. The roles of IL-17A in inflammatory immune responses and host defense against pathogens. Immunol Rev. 2008 Dec;226:57-79.
[4]McGeachy MJ, et al. The IL-17 Family of Cytokines in Health and Disease. Immunity. 2019 Apr 16;50(4):892-906.
[5]Iyoda M, et al. IL-17A and IL-17F stimulate chemokines via MAPK pathways (ERK1/2 and p38 but not JNK) in mouse cultured mesangial cells: synergy with TNF-alpha and IL-1beta. Am J Physiol Renal Physiol. 2010 Mar;298(3):F779-87.
Smiles AAIIPQSSAC PNTEAKDFLQ NVKVNLKVFN SLGAKVSSRR PSDYLNRSTS PWTLHRNEDP DRYPSVIWEA QCRHQRCVNA EGKLDHHMNS VLIQQEILVL KREPESCPFT FRVEKMLVGV GCTCVASIVR QAA&RKNPKA GVPALQKAGN CPPLEDNTVR VDIRIFNQNQ GISVPREFQN RSSSPWDYNI TRDPHRFPSE IAEAQCRHSG CINAQGQEDS TMNSVAIQQE ILVLRREPQG CSNSFRLEKM LLKVGCTCVK PIVHQAA
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias IL-17A-17F Heterodimer Protein, Mouse (Biotinylated, HEK293, His-Avi),Mouse,HEK293
Available
Product Description
IL-17A-17F Heterodimer Protein is the heterodimer of the cytokines IL-17A and IL-17F. Both IL-17A and IL-17F can induce antimicrobial peptides, cytokines (IL-6 and GM-CSF), chemokines (CCL2, CCL7 and CXCL1), and matrix metalloproteinases (MMP-1 and MMP13). IL-17A-17F shows intermediate biological activity between IL-17A and IL-17F[1][2][3][4]. IL-17A-17F Heterodimer Protein, Mouse (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant mouse IL-17A-17F heterodimer protein with His tag and Avi tag at the C-terminus and is expressed in HEK293 cells. It consists of 266 amino acids (IL-17A (A26-A158) & IL-17F (R29-A161)).
StorageTemperature
Stored at -20°C for 2 years
Shipping
Blue Ice
Molecular Weight
22-25 kDa & 27-30 kDa
Manufacturers Product type
Recombinant Proteins

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
Listprice: €1,087.00
Price: €1,087.00
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