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IL-1R2 Protein, Cynomolgus (HEK293, Fc) European Partner

€177.00
Excl. VAT
Item no. HY-P77410-50ug
Manufacturer MedChem Express
Amount 50 ug
Category
Type Proteins Recombinant
Specific against other
Purity 98.0
Citations [1]Molgora M, et al. Tuning inflammation and immunity by the negative regulators IL-1R2 and IL-1R8. Immunol Rev. 2018 Jan;281(1):233-247.
[2]PetersVA,etal.IL-1receptor2(IL-1R2)anditsroleinimmuneregulation.BrainBehavImmun.2013Aug;32:1-8.
[3]Lin J, et al. Cardiomyocyte IL-1R2 protects heart from ischemia/reperfusion injury by attenuating IL-17RA-mediated cardiomyocyte apoptosis. Cell Death Dis. 2022 Jan 27;13(1):90.
Smiles FTLQPAAHT GAARSCRFRG RHYKREFRLE GEPVALRCPQ VPYRLWASVS PHINLTWHKN DSARMVPGEE ETRMWAQDGA LWLLPALQED SGTYICTTRN ASYCDKVSIE LRVFENTDAS LPFISYPQIL TLSTSGVLVC PDLREFTRDK TDVKIQWYKD SLPLDKDNEK FLSVRGTTHL LVHDVALEDA GYYRCVLTFA HEGQQYNITR TVELRIKKKK EETIPVIISP LKTISASLGS RLTIPCKVFL GTGTPLTTML WWTANDTHVE SAYPGGRVTE GPRQEYSENN ENYIEVPLIF DPVTREDLNM DFKCVVRNTL GFQTLRTTVK E
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias IL-1R2 Protein, Cynomolgus (HEK293, Fc),Cynomolgus,HEK293
Available
Product Description
IL-1R2 is a competitive endogenous inhibitor of IL-1 signaling. IL-1R2 serves as a decoy receptor and competes with IL-1R1 for IL-1, it can also form a complex with IL-1RAP once it binds IL-1. IL-1R2 is implicated in various IL-1-mediated inflammatory diseases[1]. IL-1R2 Protein, Cynomolgus (HEK293, Fc) is a recombinant cynomolgus IL-1R2 protein with an hFc tag at the C-terminus and is expressed in HEK293 cells. It consists of 343 amino acids (M1-E343).
StorageTemperature
Stored at -20°C for 2 years
Shipping
Blue Ice
Molecular Weight
Approximately 80-95 kDa
Manufacturers Product type
Recombinant Proteins

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
Listprice: €177.00
Price: €177.00
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