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IL-12R beta 2 Protein, Mouse (HEK293, Fc)

IL-12R beta 2 Protein, Mouse (HEK293, Fc)

Item no.	HY-P72596-100mg
Manufacturer	MedChem Express
Amount	100 mg
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Citations	[1]Ryuta Nishikomori, et al. Activated STAT4 has an essential role in Th1 differentiation and proliferation that is independent of its role in the maintenance of IL-12R beta 2 chain expression and signaling. J Immunol. 2002 Oct 15;169(8):4388-98. [2]Xuefang Cao, et al. Interleukin 12 stimulates IFN-gamma-mediated inhibition of tumor-induced regulatory T-cell proliferation and enhances tumor clearance. Cancer Res. 2009 Nov 15;69(22):8700-9. [3]Gaëlle Chognard, et al. The dichotomous pattern of IL-12r and IL-23R expression elucidates the role of IL-12 and IL-23 in inflammation. PLoS One. 2014 Feb 21;9(2):e89092. [4]Esther van de Vosse, et al. IL-12Rβ1 deficiency: mutation update and description of the IL12RB1 variation database. Hum Mutat. 2013 Oct;34(10):1329-39.
Smiles	MAQTVRECSL ALLFLFMWLL IKANIDVCKL GTVTVQPAPV IPLGSAANIS CSLNPKQGCS HYPSSNELIL LKFVNDVLVE NLHGKKVHDH TGHSSTFQVT NLSLGMTLFV CKLNCSNSQK KPPVPVCGVE ISVGVAPEPP QNISCVQEGE NGTVACSWNS GKVTYLKTNY TLQLSGPNNL TCQKQCFSDN RQNCNRLDLG INLSPDLAES RFIVRVTAIN DLGNSSSLPH TFTFLDIVIP LPPWDIRINF LNASGSRGTL QWEDEGQVVL NQLRYQPLNS TSWNMVNATN AKGKYDLRDL RPFTEYEFQI SSKLHLSGGS WSNWSESLRT RTPEEEPVGI LDIWYMKQDI DYDRQQISLF WKSLNPSEAR GKILHYQVTL QEVTKKTTLQ NTTRHTSWTR VIPRTGAWTA SVSAANSKGA SAPTHINIVD LCGTGLLAPH QVSAKSENMD NILVTWQPPK KADSAVREYI VEWRALQPGS ITKFPPHWLR IPPDNMSALI SENIKPYICY EIRVHALSES QGGCSSIRGD SKHKAPVSGP HITAITEKKE RLFISWTHIP FPEQRGCILH YRIYWKERDS TAQPELCEIQ YRRSQNSHPI SSLQPRVTYV LWMTAVTAAG ESPQGNEREF CPQGKAN
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IL-12R beta 2 Protein, Mouse (HEK293, Fc),Mouse,HEK293
Available
Product Description	IL-12R beta 2 protein is an IL-12 cytokine surface receptor that activates the Jak-Stat signaling cascade pathway and is involved in IL-12-mediated immune regulation. IL-12R beta 2 Protein, Mouse (HEK293, Fc) is expressed by HEK 293 cells with a transmembrane region (W638-I658) and a hFc tag at the C-terminus[1].
Shipping	Room temperature
Molecular Weight	125-160 kDa
Manufacturers Product type	Recombinant Proteins

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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