RSPO1/R-spondin-1 Protein, Mouse (189aa, His)

RSPO1 activates the canonical Wnt signaling pathway by binding to LGR4-6 receptors, triggering increased expression of target genes. It inhibits ZNRF3, regulating the Wnt signaling pathway, and negatively regulates the TGF-beta pathway. RSPO1 also plays a role in ovary determination and interacts with various proteins including FZD8, LRP6, and WNT1. It forms complexes with RNF43, LGR5, and LGR6, and promotes membrane clearance of ZNRF3. RSPO1 binds heparin and interacts with LGR4, LGR5, and LGR6. RSPO1/R-spondin-1 Protein, Mouse (189aa, His) is the recombinant mouse-derived RSPO1/R-spondin-1 protein, expressed by E. coli, with N-6*His labeled tag. The total length of RSPO1/R-spondin-1 Protein, Mouse (189aa, His) is 189 a.a., with molecular weight of ~23 kDa.

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Recombinant Proteins