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Biotinylated Human HLA-A*02:01&B2M&p53 (HMTEVVRHC) Complex Protein (Monomer, MALS verified)

Biotinylated Human HLA-A*02:01&B2M&p53 (HMTEVVRHC) Complex Protein (Monomer, MALS verified)

€875.00

Excl. VAT

Item no.	HLP-H82E3-200ug
Manufacturer	ACROBiosystems
Amount	200ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens)
Conjugate/Tag	Biotin-labeled; C-10×His; C-Avi
Purity	0,95
Dry ice	Yes
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Description	TP53 has been recognized as a tumor suppressor. 50% of cancers carry a TP53 mutation while many others affect other pathway components. High-copy numbers of WT p53 peptide-MHC class I complexes were detected on tumor cells as compared to low copies on normal cells. The Human HLA-A0201 p53 (GLAPPQHLIRV) complex protein is a complex of HLA-A0201 of the MHC Class I, B2M, and GLAPPQHLIRV peptide of the p53.
Characteristics	Biotinylated Human HLA-A*02:01&B2M&p53 (HMTEVVRHC) Complex Protein is produced by co-expression of HLA and B2M loaded with p53 peptide. This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 36.3 kDa and 11.7 kDa. The protein migrates as 38-43 kDa and 12 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Molecule	HLA-A*0201 & B2M & p53 (HMTEVVRHC)
Molecular Weight	36.3 kDa and 11.7 kDa
Expression System	HEK293
Exp Region	Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & HMTEVVRHC peptide
Endotoxin Level	1.0 EU per μg
Buffer	PBS, pH7.4
Storage	-70℃

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200ug

Listprice: €875.00

Price: €875.00

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Delivery expected until 9/4/2025

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