Mouse TIM3 Protein, hFc Tag

€493.00

Excl. VAT

Item no.	DIM-PME-M100048-50ug
Manufacturer	DIMA Biotechnology
Amount	50ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Conjugate/Tag	C-Human Fc tag
Purity	The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	HAVCR2, TIMD3, FLJ14428, KIM3
Available
Background	The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]
Description	Recombinant mouse TIM3 protein with C-terminal human Fc tag
Expression Host	HEK293
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Molecular Weight	The protein has a predicted molecular mass of 45.4 kDa after removal of the signal peptide. The apparent molecular mass of mTIM3-hFc is approximately 55-70 kDa due to glycosylation.
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized proteins are shipped at ambient temperature.
Usage	Research use only

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ug

Listprice: €493.00

Price: €493.00

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Delivery expected until 10/2/2025

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