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Human CD3 epsilon&CD3 delta Heterodimer Protein, Fc,His Tag&Fc,Flag Tag (MALS verified) European Partner

€742.00
Excl. VAT
Item no. CDD-H52Wa-100ug
Manufacturer ACROBiosystems
Amount 100ug
Category
Type Proteins Recombinant
Format Powder
Specific against Human (Homo sapiens)
Conjugate/Tag His; Fc; FLAG
Purity >95% as determined by SDS-PAGE.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Available
Bioactivity Legend 1
Immobilized Human CD3E&CD3D Heterodimer Protein (Cat. No. CDD-H52Wa) at 1 ?g/mL (100 ?L/well) can bind Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (Clone: OKT3), Ultra-low endotoxin (Cat. No. CDE-M120a) with a linear range of 0.2-3 ng/mL (QC tested).
Bioactivity Legend 2
Immobilized Human CD3E&CD3D Heterodimer Protein (Cat. No. CDD-H52Wa) at 1 ?g/mL (100 ?L/well) can bind UCHT1 with a linear range of 0.1-3 ng/mL (Routinely tested).
Buffer
PBS, pH7.4
Characteristics
Human CD3E&CD3D Heterodimer Protein is produced by co-expression of CD3E and CD3D, has a calculated MW of 40.2 kDa (CD3E) and 37.3 kDa (CD3D). The reducing (R) protein migrates as 45-55 kDa due to glycosylation.
Description
T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Endotoxin Level
Less than 1.0 EU per ?g by the LAL method.
Exp Region
Asp 23 - Asp 126 (CD3E) & Phe 22 - Ala 105 (CD3D)
Expression System
HEK293
Molecular Weight
40.2 kDa | 37.3 kDa
Molecule
CD3E & CD3D
SDS-PAGE Legend
Human CD3E&CD3D Heterodimer Protein on SDS-PAGE under reducing (R) and non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Storage
-20?

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100ug
Available: In stock
Listprice: €742.00
Price: €742.00
available

Delivery expected until 9/18/2025 

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