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Human CD133 Protein, His Tag

Human CD133 Protein, His Tag

€7,405.00

Excl. VAT

Item no.	CD3-H52H4-500ug
Manufacturer	ACROBiosystems
Amount	500ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	His
Purity	>90% as determined by SDS-PAGE.
Dry ice	Yes
Citations	(1) Takenobu H, et al. 2011. Oncogene. 30(1):97-105. (2) Mak AB, et al. 2014. J Mol Biol. 426(11):2175-82.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD133,PROM1,PROML1,Prominin-1,AC133
Available
Bioactivity Legend 1	Immobilized Human CD133, His Tag (Cat. No. CD3-H52H4) at 1 ug/mL (100 uL/well) can bind Monoclonal Anti-Human CD133 (133-3) Antibody, Human IgG1 with a linear range of 1-16 ng/mL (QC tested).
Buffer	50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 97.2 kDa. The protein migrates as 90-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Description	Prominin-1 is also known as CD133, Antigen AC133, PROM1, PROML1 and MSTP061. Is used as marker for hematopoietic stem and progenitor cells (HSPC) for somatic stem cell isolation. May play a role in cell differentiation, proliferation and apoptosis . Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.
Endotoxin Level	Less than 1.0 EU per ug by the LAL method.
Exp Region	Gly 20 - His 865
Expression System	HEK293
Molecular Weight	97.2 kDa
Molecule	CD133
SDS-PAGE Legend	Human CD133, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Storage	-70C
Host Information	Human CD133, His Tag (CD3-H52H4) is expressed from human 293 cells (HEK293). It contains AA Gly 20 - His 865 (Accession # O43490-1).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500ug

Listprice: €7,405.00

Price: €7,405.00

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Delivery expected until 9/11/2025

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