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Biotinylated Human B7-H4 Protein, Avitag,His Tag (recommended for biopanning)

Biotinylated Human B7-H4 Protein, Avitag,His Tag (recommended for biopanning)

€1,685.00

Excl. VAT

Item no.	B74-H82E2-200ug
Manufacturer	ACROBiosystems
Amount	200ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Powder
Specific against	Human (Homo sapiens)
Conjugate/Tag	His; AVI
Purity	>90% as determined by SDS-PAGE.
Citations	(1) Salceda S., et al., 2005, Exp. Cell Res. 306:128-141. (2) Kryczek I., et al., 2006, J. Exp. Med. 203:871-881. (3) Miyatake T., et al., 2007, Gynecol. Oncol. 106:119-127.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	B7-H4,VTCN1,B7S1,B7h.5
Available
Buffer	PBS, pH7.4
Characteristics	This protein carries an Avi tag (Avitag) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 28 kDa. The protein migrates as 45-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Description	V-set domain-containing T-cell activation inhibitor 1 (VTCN1) is also known as Immune costimulatory protein B7-H4, Protein B7S1, T-cell costimulatory molecule B7x, B7H4, which belongs to the immunoglobulin superfamily and BTN/MOG family. VTCN1 contains two Ig-like V-type (immunoglobulin-like) domains. The expression of VTCN1 is up-regulated by IL6 and IL10 and is inhibited by GM-CSF and IL4 on antigen-presenting cells (APCs). VTCN1 / B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. VTCN1 involved in promoting epithelial cell transformation.
Endotoxin Level	Less than 1.0 EU per ug by the LAL method.
Exp Region	Phe 29 - Ala 258
Expression System	HEK293
Molecular Weight	28 kDa
Molecule	B7-H4
Shipping Conditions	RT
Storage	-20C

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200ug

Listprice: €1,685.00

Price: €1,685.00

available

Delivery expected until 11/13/2025

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