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ACE2 Protein, Human, Recombinant (His Tag), HPLC-verified

ACE2 Protein, Human, Recombinant (His Tag), HPLC-verified

€600.00

Excl. VAT

Item no.	10108-H08B-100
Manufacturer	Sino Biological
Amount	100ug
Category	Neuroscience Aging & Neurological Disorders Infectious Diseases Viral Infections Coronavirus (COVID-19) Peptides & Proteins Recombinant Proteins Cardiovascular Research Heart Failure Myocardial Infarction
Type	Proteins
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Purity	> 93 % as determined by SDS-PAGE. > 95 % as determined by SEC-HPLC.
Endotoxin	< 1.0 EU per ug protein as determined by the LAL method.
Activity	Measured by its binding ability in a functional ELISA. Immobilized 2019-nCoV Spike Protein (RBD, mFc Tag)(40592-V05H) at 2ug/mL (100uL/well) can bind human ACE2 protein (10108-H08B), the EC50 of human ACE2 protein (10108-H08B)is 10-35ng/mL.
Protein Construction	A DNA sequence encoding the human ACE2 (NP_068576.1) (Met1-Ser740) was expressed with a polyhistidine tag at the C-terminus.
Expressed Host	Baculovirus-Insect Cells
Predicted N Terminal	Gln 18
Molecule Mass	The recombinant human ACE2 consists of 734 amino acids and predicts a molecular mass of 85.1 kDa.
Formulation	Lyophilized from sterile 20mM PBS, 300mM NaCl, 10% glycerol, pH 7.0. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability and Storage	Samples are stable for up to twelve months from date of receipt at -20C to -80C Store it under sterile conditions at -20C to -80C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
References	Koitka A, et al. (2008) Angiotensin converting enzyme 2 in the kidney. Clin Exp Pharmacol Physiol. 35(4): 420-5. Raizada MK, et al. (2007) ACE2: a new target for cardiovascular disease therapeutics. J Cardiovasc Pharmacol. 50(2): 112-9. Imai Y, et al. (2007) Angiotensin-converting enzyme 2 (ACE2) in disease pathogenesis. Circ J. 74(3): 405-10. Turner AJ, et al. (2004) ACE2: from vasopeptidase to SARS virus receptor. Trends Pharmacol Sci. 25(6): 291-4.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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10108-H08B-100-datasheet.pdf

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Amount: 100ug

Listprice: €600.00

Price: €600.00

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Delivery expected until 9/4/2025

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