Comparison

gp100 209-217 mutant (HLA-A*02:01) 210M European Partner

€58.00
Excl. VAT
Item no. EP07860_1
Manufacturer peptides & elephants
Amount 1 mg
Category
Type Peptides
Specific against Human (Homo sapiens)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias IMDQVPFSV Melanocyte protein PMEL HLA-A*02:01 Cancer, Epithelium, Melanoma T-cell assays, Immune monitoring, Antigen specific T-cell stimulation, T-cell expansion, Cellular immune response
Available
Description
gp100 209-217 Pos. 210M (HLA-A*02:01) IMDQVPFSV is a linear peptidic epitope studied as part of Melanoma antigen preferentially expressed in tumors from Homo sapiens (human). This epitope has been studied for immune reactivity in several publication, tested in T cell assays and MHC ligand assays.

This modified gp100 peptide amino acids 209 to 217 is a MHC-associated HLA-A2.1-restricted epitope derived from melanoma antigene. It can be processed, presented, and recognized by T cells. Alteration of the gp100 209-217 peptide to gp100 209-217 Met2 at the second amino acid changing threonine to a methionine was found to increase the affinity for MHC-associated HLA-A2.1 resulting in enhanced induction of T cells reactive to native gp100
Keywords
IMDQVPFSV Melanocyte protein PMEL HLA-A*02:01 Cancer, Epithelium, Melanoma T-cell assays, Immune monitoring, Antigen specific T-cell stimulation, T-cell expansion, Cellular immune response
Sequence
IMDQVPFSV
N-Terminus
H
C-Terminus
OH
Purity
0, 95
Counter-Ion
TFA
Protein
Melanocyte protein PMEL
Gene
PMEL
Allele
HLA-A*02:01
Application
T-cell assays, Immune monitoring, Antigen specific T-cell stimulation, T-cell expansion, Cellular immune response
Indication
Cancer, Epithelium, Melanoma
Storage
Store dry at -20°C

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mg
Available: In stock
Listprice: €58.00
Price: €58.00
available

Delivery expected until 9/18/2025 

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