JavaScript seems to be disabled in your browser. You must have JavaScript enabled in your browser to utilize the functionality of this website.
Description: Bromodeoxyuridine (BrdU; Broxuridine; 5-Bromo-2'-deoxyuridine; BUdR) is a nucleoside analog with potential anticancer activity. It acts as an antimetabolite anticancer agent by competing with thymidine for incorporation into DNA, and has been used in the detection of proliferating cells. The effect of 5-BrdU on the proliferation was studied in the early phases of dedifferentiation of Nicotiana glauca pith explants grown. It was found to be wholly inhibitory only when given during the first 72 h of culture, this inhibition being reversed by simultaneous addition of either deoxyeytidine or thymidine.
References: Neoplasia. 2008 Aug; 10(8):804-16; Curr Protoc Cytom. 2007 Apr; Chapter 7:Unit7.31.
Chemical Name: 5-Bromo-2'-deoxyuridine
InChi Key: WOVKYSAHUYNSMH-RRKCRQDMSA-N
InChi Code: InChI=1S/C9H11BrN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2, 5-7, 13-14H, 1, 3H2, (H, 11, 15, 16)/t5-, 6+, 7+/m0/s1
SMILES Code: OC[CH]1[CH](C[CH](N2C(NC(C(Br)=C2)=O)=O)O1)O
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
Request Data Sheet
Request product datasheet
Request safety datasheet
Delivery expected until 10/2/2025
Compare
Add to wishlist
Get an offer
Request delivery time
Ask a technical question
Submit a bulk request
sales@hoelzel.de
« Back
Subscribe, get 15% off every fifth order and have your items delivered on time!
Forgot Your Password?
Not yet registered? Create account here!