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Halofuginone hydrobromide

Halofuginone hydrobromide

€34.00

Excl. VAT

Item no.	TMO-T3524-1mg
Manufacturer	TargetMol
CASRN	64924-67-0
Amount	1mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Format	Powder
Specific against	other
Purity	0,9701
Smiles	Br.O[C@@H]1CCCN[C@H]1CC(=O)Cn1cnc2cc(Br)c(Cl)cc2c1=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	64924-67-0, Tempostatin , RU-19110 (hydrobromide) , Stenorol
Available
Short Description	Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor cell growth. Halofuginone Hydrobromide is the hydrobromide salt of halofuginone, a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities. These effects appear to be due to halofuginone-mediated inhibition of the collagen type I and MMP-2 promoters. Collagen type I and MMP-2 play important roles in fibroproliferative diseases.
Shipping	cool pack
Storage	-20°
Target names or alias	Tempostatin , RU-19110 (hydrobromide) , Stenorol
Molecular Weight	495, 59
Pathway	Cell Cycle/Checkpoint\|\|\|DNA Damage/DNA Repair\|\|\|Metabolism\|\|\|Microbiology/Virology\|\|\|Stem Cells\|\|\|Membrane transporter/Ion channel\|\|\|Others
Target	Others\|\|\|Parasite\|\|\|TGF-beta/Smad\|\|\|DNA/RNA Synthesis\|\|\|Calcium Channel\|\|\|Sodium Channel

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1mg

Listprice: €34.00

Price: €34.00

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Delivery expected until 8/28/2025

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