« Back
Home /
PI3Kα/mTOR-IN-1

PI3Kα/mTOR-IN-1

€1,501.00

Excl. VAT

Item no.	HY-U00326-1mg
Manufacturer	MedChem Express
CASRN	1013098-90-2
Amount	1 mg
Category	Oncology By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Adenocarcinoma Mesothelioma Autophagy Cardiovascular Research Proliferation Myocardial Infarction Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Formula	C16H18N6O
Citations	[1]Le PT, et al. Design and synthesis of a novel pyrrolidinyl pyrido pyrimidinone derivative as a potent inhibitor of PI3Kα and mTOR. Bioorg Med Chem Lett. 2012 Aug 1;22(15):5098-103.
Smiles	O=C1C(C2=CNN=C2)=CC3=C(C)N=C(N)N=C3N1C4CCCC4
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1013098-90-2
Available
Product Description	PI3Kα/mTOR-IN-1 is a potent PI3Kα/mTOR dual inhibitor, with an IC50 of 7 nM for PI3Kα in a cell assay, and Kis of 10.6 nM and 12.5 nM for mTOR and PI3Kα in a cell free assay , respectively.
Shipping	Room temperature
Manufacturers Applications	Cancer-Kinase/protease
Molecular Weight	310.35
Clinical Information	No Development Reported
Solubility	10 mM in DMSO
Isoform	mTOR; PI3Kα
Pathway	PI3K/Akt/mTOR
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 1 mg

Listprice: €1,501.00

Price: €1,501.00

available

Quantity:

Compare

Add to wishlist