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IL-19 Protein, Mouse

IL-19 Protein, Mouse

€187.00

Excl. VAT

Item no.	HY-P7213-10ug
Manufacturer	MedChem Express
Amount	10 ug
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	95.00
Citations	[1]IL-19 shares 21% amino acid identity with IL-10. The exon/intron structure of IL-19 is similar to that of the human IL-10 gene, comprising five exons and four introns within the coding region of the IL-19 cDNA. IL-19 does not bind or signal through the canonical IL-10 receptor complex<sup>[1]</sup>. IL-19 functions through a receptor complex composed of IL-20Ra and IL20Rb that is also utilized by IL-20 and IL-24. IL19 has been shown to enhance the production of Th2 cytokines in Tcells and to be elevated in asthma patients. Furthermore, it induces IL-6, IL-8 and IL-10 expression in monocytes. Additionally, it has been implicated in a range of diseases and disorders, including aging, Type-I diabetes, endotoxic shock, periodontal disease, vascular disease and rheumatoid arthritis<sup>[2]</sup>. [2]Gallagher G, et al. Interleukin-19: multiple roles in immune regulation and disease. Cytokine Growth Factor Rev. 2010 Oct;21(5):345-52.
Smiles	MLRRCLISVD MRLIEKSFHE IKRAMQTKDT FKNVTILSLE NLRSIKPGDV CCMTNNLLTF YRDRVFQDHQ ERSLEVLRRI SSIANSFLCV QKSLERCQVH RQCNCSQEAT NATRIIHDNY NQLEVSSAAL KSLGELNILL AWIDRNHLET PAA
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	IL-19 Protein, Mouse,Mouse,E. coli
Available
Product Description	IL-19 Protein, Mouse is a member of the Interleukin-10 family. The biological functions and clinical implications of Interleukin-19 is still undefined.
StorageTemperature	Stored at -20°C for 2 years
Shipping	Blue Ice
Molecular Weight	Approximately 17.7 kDa
Manufacturers Product type	Recombinant Proteins

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

Listprice: €187.00

Price: €187.00

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