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Luteolin 7-O-glucuronide

Luteolin 7-O-glucuronide

€97.00

Excl. VAT

Item no.	HY-N1463-5mg
Manufacturer	MedChem Express
CASRN	29741-10-4
Amount	5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.80
Formula	C21H18O12
Citations	[1]Crascì L, et al. Correlating In Vitro Target-Oriented Screening and Docking: Inhibition of Matrix Metalloproteinases Activities by Flavonoids. Planta Med. 2017 Jul;83(11):901-911. [2]Cho YC, et al. Anti-Inflammatory and Anti-Oxidative Effects of luteolin-7-O-glucuronide in LPS-Stimulated Murine Macrophages through TAK1 Inhibition and Nrf2 Activation. Int J Mol Sci. 2020 Mar 16;21(6):2007. [3]Ryu D, et al. Luteolin-7-O-Glucuronide Improves Depression-like and Stress Coping Behaviors in Sleep Deprivation Stress Model by Activation of the BDNF Signaling. Nutrients. 2022 Aug 12;14(16):3314.
Smiles	O[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O1)O)O)[C@@H]1OC2=CC(O)=C3C(C=C(C4=CC=C(O)C(O)=C4)OC3=C2)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Luteolin 7-glucuronide
Available
Product Description	Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively[1].
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
Molecular Weight	462.36
Clinical Information	No Development Reported
Solubility	DMSO : 125 mg/mL (ultrasonic)
Isoform	MMP-1; MMP-13; MMP-3; MMP-8; MMP-9
Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Natural Products

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HY-N1463-5mg-safety-datasheet.pdf