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Harpagoside

Harpagoside

€108.00

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Item no.	HY-N0396-10mg
Manufacturer	MedChem Express
CASRN	19210-12-9
Amount	10 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.41
Formula	C24H30O11
Citations	[1]Li J, et al. Harpagoside ameliorates the amyloid-β-induced cognitive impairment in rats via up-regulating BDNF expression and MAPK/PI3K pathways. Neuroscience. 2015 Sep 10;303:103-14. [2]Anauate MC, et al. Effect of isolated fractions of Harpagophytum procumbens D.C. (devil's claw) on COX-1, COX-2 activity and nitric oxide production on whole-blood assay. Phytother Res. 2010 Sep;24(9):1365-9. [3]Huang TH, et al. Harpagoside suppresses lipopolysaccharide-induced iNOS and COX-2 expression through inhibition of NF-kappa B activation. J Ethnopharmacol. 2006 Mar 8;104(1-2):149-55.
Smiles	O[C@H]1[C@H](O)[C@@H](O)[C@]([H])(O[C@@H]2OC=C[C@]3(O)[C@@]2([H])[C@@](C)(OC(/C=C/C4=CC=CC=C4)=O)C[C@H]3O)O[C@@H]1CO
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	19210-12-9
Available
Product Description	Harpagoside can be obtained by Harpagophytum procumbens, which has anti-inflammatory, anti-cancer, protective activity, and efficacy. Harpagoside has an inhibitory effect on COX-1 and COX-2 active, and suppresses NO production. Harpagoside inhibits HepG2 cell lipid polysaccharide, which is a protein that is expressed horizontally and selectively, and has anti-inflammatory and latent pain effects. Harpagoside has the ability to protect the body, and has a degenerative effect on the β-oxidation (Aβ)[1][2][3].
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
Molecular Weight	494.49
Clinical Information	No Development Reported
Solubility	DMSO : 62.5 mg/mL (ultrasonic)
Isoform	COX-1; COX-2
Pathway	Immunology/Inflammation
Manufacturers Product type	Natural Products

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

Listprice: €108.00

Price: €108.00

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