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Saikosaponin D

Saikosaponin D

€76.00

Excl. VAT

Item no.	HY-N0250-10mM
Manufacturer	MedChem Express
CASRN	20874-52-6
Amount	10 mM/1 mL
Category	Food Safety Hormones Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Neural Transcription Factors Neural Signaling Neural Adhesion Molecules Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Purity	98.76
Formula	C42H68O13
Citations	[1]Jang MJ, et al. Saikosaponin D isolated from Bupleurum falcatum inhibits selectin-mediated cell adhesion. Molecules. 2014 Dec 4;19(12):20340-9. [2]Liu A, et al. Saikosaponin d protects against acetaminophen-induced hepatotoxicity by inhibiting NF-κB and STAT3 signaling. Chem Biol Interact. 2014 Nov 5;223:80-6. [3]Que R, et al. Estrogen receptor-β-dependent effects of saikosaponin‑d on the suppression of oxidative stress-induced rat hepatic stellate cell activation. Int J Mol Med. 2018 Mar;41(3):1357-1364.
Smiles	CC1(C)CC[C@]2(CO3)[C@H](O)C[C@@]4(C)[C@]([C@]5([H])C=C[C@]43[C@]2([H])C1)(C)CC[C@@]([C@]5(C)CC6)([H])[C@@](CO)(C)[C@H]6O[C@@](O[C@H](C)[C@@H]7O)([H])[C@H](O)[C@H]7O[C@@]8([H])[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O8
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	20874-52-6
Available
Product Description	Saikosaponin D is a triterpene saponin isolated from Bupleurum, with anti-inflammatory, anti-bacterial, anti-tumor, and anti-allergic activities; Saikosaponin D inhibits selectin, STAT3 and NF-kB and activates estrogen receptor-β.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
Molecular Weight	780.98
Clinical Information	No Development Reported
Solubility	DMSO : 50 mg/mL (ultrasonic)\|H2O : 1 mg/mL (ultrasonic; warming; heat to 60°C)
Isoform	ERβ; NF-κB; STAT3
Pathway	Anti-infection; JAK/STAT Signaling; NF-κB; Stem Cell/Wnt; Vitamin D Related/Nuclear Receptor
Manufacturers Product type	Natural Products

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-N0250-10mM-safety-datasheet.pdf