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Monensin sodium salt

Monensin sodium salt

€54.00

Excl. VAT

Item no.	HY-N0150-10mM
Manufacturer	MedChem Express
CASRN	22373-78-0
Amount	10 mM/1 mL
Category	Food Safety Antibiotics Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Purity	98.0
Formula	C36H61NaO11
Citations	bioRxiv. 2023 Sep 12. Front Microbiol. 2020 Apr 30;11:790. Int Immunopharmacol. 2023 Sep 1;124(Pt A):110865. J Exp Med. 2023 Mar 6;220(3):e20221316. Nat Commun. 2022 Jul 22;13(1):4255. Research Square Preprint. 2023 Aug 31. AAPS PharmSciTech. 2023 Feb 15;24(2):69. Biochem Pharmacol. 2023 Dec 2:115957. Clin Exp Immunol. 2023 Dec 26:uxad137. Clin Immunol. 2022: 109217. Int J Parasitol Drugs Drug Resist. 2023 Aug, 22, 44-51. J Exp Clin Cancer Res. 2021 Jan 6;40(1):16. Nat Methods. 2023 Dec 4. OncoImmunology. 2023 Apr 19. Redox Biol. 2022 Aug 27;56:102456. Signal Transduct Target Ther. 2023 Jul 17;8(1):273. Small. 2021 Nov 1;e2103984. [1]Ariel Savina, et al. Rab11 promotes docking and fusion of multivesicular bodies in a calcium-dependent manner. Traffic. 2005 Feb;6(2):131-43. [2]Youhua Huang, et al. Autophagy Participates in Lysosomal Vacuolation-Mediated Cell Death in RGNNV-Infected Cells. Front. Microbiol., 30 April 2020. [3]Tumova L, et al. Monensin inhibits canonical Wnt signaling in human colorectal cancer cells and suppresses tumor growth in multiple intestinal neoplasia mice. Mol Cancer Ther. 2014 Apr;13(4):812-22. [4]Dayekh K, et al. Monensin inhibits epidermal growth factor receptor trafficking and activation: synergistic cytotoxicity in combination with EGFR inhibitors. Mol Cancer Ther. 2014 Nov;13(11):2559-71.
Smiles	OC[C@@]1(O)[C@H](C)C[C@H](C)[C@]([C@@]2(O[C@]([C@@]3(CC[C@@]([C@]4(O[C@@]5(C[C@H](O)[C@@H](C)[C@@]([H])([C@H]([C@@H](OC)[C@H](C)C(O[Na])=O)C)O5)CC4)C)([H])O3)CC)([H])[C@@H](C)C2)[H])([H])O1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Monensin A sodium salt
Available
Product Description	Monensin sodium salt is an antibiotic secreted by the bacteria Streptomyces cinnamonensis. Monensin sodium salt is an ionophore that mediates Na+/H+ exchange. Monensin sodium salt causes a marked enlargement of the multivesicular bodies (MVBs) and regulates exosome secretion[1][2][3][4].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
Molecular Weight	692.85
Clinical Information	No Development Reported
Solubility	Ethanol : 20 mg/mL (ultrasonic)
Pathway	Anti-infection; Membrane Transporter/Ion Channel
Manufacturers Product type	Natural Products

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-N0150-10mM-safety-datasheet.pdf