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Dexamethasone phosphate disodium

Dexamethasone phosphate disodium

€49.00

Excl. VAT

Item no.	HY-B1829A-100mg
Manufacturer	MedChem Express
CASRN	2392-39-4
Amount	100 mg
Category	Food Safety Drugs Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Purity	99.76
Formula	C22H28FNa2O8P
Citations	[1]LaLone CA, et al. Effects of a glucocorticoid receptor agonist, Dexamethasone, on fathead minnow reproduction, growth, and development. Environ Toxicol Chem. 2012 Mar;31(3):611-22. [2]Adcock IM, et al. Ligand-induced differentiation of glucocorticoid receptor (GR) trans-repression and transactivation: preferential targetting of NF-kappaB and lack of I-kappaB involvement. Br J Pharmacol. 1999 Jun;127(4):1003-11. [3]Rocksén D, et al. Differential anti-inflammatory and anti-oxidative effects of Dexamethasone and N-acetylcysteine in endotoxin-induced lung inflammation. Clin Exp Immunol. 2000 Nov;122(2):249-56. [4]Roussel D, et al. Dexamethasone treatment specifically increases the basal proton conductance of rat liver mitochondria. FEBS Lett. 2003 Apr 24;541(1-3):75-9.
Smiles	O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@]2(F)[C@@H](O)C[C@@]4(C)[C@@]3([H])C[C@@H](C)[C@]4(O)C(COP(O[Na])(O[Na])=O)=O)=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Dexamethasone 21-phosphate (disodium)
Available
Product Description	Dexamethasone phosphate (Dexamethasone 21-phosphate) disodium is an orally active Glucocorticoid receptor agonist[1].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
Molecular Weight	516.40
Clinical Information	Launched
Solubility	DMSO : 1 mg/mL (ultrasonic; warming; heat to 80°C)\|H2O : ≥ 100 mg/mL
Pathway	Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Manufacturers Product type	Reference compound

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HY-B1829A-100mg-safety-datasheet.pdf