« Back
Home /
Corticosterone

Corticosterone

€54.00

Excl. VAT

Item no.	HY-B1618-10mM
Manufacturer	MedChem Express
CASRN	50-22-6
Amount	10 mM/1 mL
Category	Metabolism Diabetes Glucose Homeostasis Obesity Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	99.70
Formula	C21H30O4
Citations	[1]Elftman MD, et al. Corticosterone impairs dendritic cell maturation and function. Immunology. 2007 Oct;122(2):279-90. [2]Schaaf MJ, et al. Downregulation of BDNF mRNA and protein in the rat hippocampus by corticosterone. Brain Res. 1998 Nov 30;813(1):112-20. [3]Fahlke C, et al. Involvement of corticosterone in the modulation of ethanol consumption in the rat. Alcohol. 1994 May-Jun;11(3):195-202.
Smiles	C[C@@]12[C@@H](C(CO)=O)CC[C@@]1([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])[C@@H](O)C2)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	17-Deoxycortisol; 11β,21-Dihydroxyprogesterone; Kendall's compound B
Available
Product Description	Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect[1][2][3][4].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
Molecular Weight	346.46
Clinical Information	Phase 3
Solubility	DMSO : 100 mg/mL (ultrasonic)\|Ethanol : 14.29 mg/mL (ultrasonic)\|H2O : 0.67 mg/mL (ultrasonic)
Isoform	AMPA Receptor; Human Endogenous Metabolite
Pathway	Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Vitamin D Related/Nuclear Receptor
Manufacturers Product type	Natural Products

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

HY-B1618-10mM-safety-datasheet.pdf