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Fexofenadine hydrochloride

Fexofenadine hydrochloride

€130.00

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Item no.	HY-B0801A-50mg
Manufacturer	MedChem Express
CASRN	153439-40-8
Amount	50 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	99.86
Formula	C32H40ClNO4
Citations	Int Immunopharmacol. 2023 Feb 8;116:109637. Adv Mater Technol. 2023 Jan 29. Pharmacol Res. 2023 Mar 10;106724. [1]Watanabe N, et al. The effects of fexofenadine on eosinophilia and systemic anaphylaxis in mice infected with Trichinella spiralis. Int Immunopharmacol. 2004 Mar;4(3):367-75. [2]Park IH, et al. Histamine Promotes the Release of Interleukin-6 via the H1R/p38 and NF-κB Pathways in Nasal Fibroblasts. Allergy Asthma Immunol Res. 2014 Nov;6(6):567-72. [3]Ming X, et al. Vectorial transport of fexofenadine across Caco-2 cells: involvement of apical uptake and basolateral efflux transporters. Mol Pharm. 2011 Oct 3;8(5):1677-86.
Smiles	O=C(O)C(C)(C)C1=CC=C(C(O)CCCN2CCC(C(C3=CC=CC=C3)(O)C4=CC=CC=C4)CC2)C=C1.[H]Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	MDL-16455 (hydrochloride); Terfenadine carboxylate (hydrochloride)
Available
Product Description	Fexofenadine (MDL-16455) hydrochloride is an orally active and nonsedative H1 receptor antagonist. Fexofenadine hydrochloride can be used in allergic rhinitis and chronic idiopathic urticarial research[1][2][3].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
Molecular Weight	538.12
Clinical Information	Launched
Solubility	DMSO : ≥ 100 mg/mL\|H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Isoform	H1 Receptor
Pathway	GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Manufacturers Product type	Reference compound

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HY-B0801A-50mg-safety-datasheet.pdf