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Probenecid

Probenecid

€65.00

Excl. VAT

Item no.	HY-B0545-1g
Manufacturer	MedChem Express
CASRN	57-66-9
Amount	1 g
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Colorectal Cancer Brain Cancer
Type	Inhibitors
Purity	99.95
Formula	C13H19NO4S
Citations	[1]Bakos E, et al. Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions. Mol Pharmacol. 2000 Apr;57(4):760-8. [2]Koch SE, et al. Probenecid: novel use as a non-injurious positive inotrope acting via cardiac TRPV2 stimulation. J Mol Cell Cardiol. 2012 Jul;53(1):134-44. [3]Greene TA, et al. Probenecid inhibits the human bitter taste receptor TAS2R16 and suppresses bitter perception of salicin. PLoS One. 2011;6(5):e20123. [4]Silverman W, et al. Probenecid, a gout remedy, inhibits pannexin 1 channels. Am J Physiol Cell Physiol. 2008 Sep;295(3):C761-7.
Smiles	O=C(O)C1=CC=C(S(=O)(N(CCC)CCC)=O)C=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	57-66-9
Available
Product Description	Probenecid is a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Probenecid also inhibits pannexin 1 channels.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Metabolism-protein/nucleotide metabolism
Molecular Weight	285.36
Clinical Information	Launched
Solubility	0.5 M NaOH : 100 mg/mL (ultrasonic; adjust pH to 12 with NaOH)\|DMSO : ≥ 100 mg/mL
Pathway	Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-B0545-1g-safety-datasheet.pdf