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Desloratadine

Desloratadine

€64.00

Excl. VAT

Item no.	HY-B0539-10mM
Manufacturer	MedChem Express
CASRN	100643-71-8
Amount	10 mM/1 mL
Category	Food Safety Histamines Neuroscience Neuroinflammation Metabolism Diabetes Glucose Homeostasis Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Purity	99.98
Formula	C19H19ClN2
Citations	[1]Geha, R.S. and E.O. Meltzer, Desloratadine: A new, nonsedating, oral antihistamine. J Allergy Clin Immunol, 2001. 107(4): p. 751-62. [2]Schroeder, J.T., et al., Inhibition of cytokine generation and mediator release by human basophils treated with desloratadine. Clin Exp Allergy, 2001. 31(9): p. 1369-77. [3]Anthes, J.C., et al., Biochemical characterization of desloratadine, a potent antagonist of the human histamine H(1) receptor. Eur J Pharmacol, 2002. 449(3): p. 229-37. [4]McClellan K, et al. Desloratadine. Drugs. 2001;61(6):789-797.
Smiles	ClC1=CC=C2C(CCC3=CC=CN=C3/C2=C4CCNCC/4)=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Sch34117
Available
Product Description	Desloratadine (Sch34117) is the orally active major metabolite of the nonsedating H1-antihistamine Loratadine. Desloratadine is a selective H1-receptor antagonist that has anti-allergic and anti-inflammatory activities[1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
Molecular Weight	310.82
Clinical Information	Launched
Solubility	DMSO : 25 mg/mL (ultrasonic)\|H2O : 0.67 mg/mL (ultrasonic)
Isoform	H1 Receptor; Human Endogenous Metabolite
Pathway	GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling
Manufacturers Product type	Natural Products

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-B0539-10mM-safety-datasheet.pdf