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Moclobemide

Moclobemide

€54.00

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Item no.	HY-B0534-10mM
Manufacturer	MedChem Express
CASRN	71320-77-9
Amount	10 mM/1 mL
Category	Oncology Metabolism Diabetes Glucose Homeostasis Inhibitors & Compound Libraries Small Molecules By Organ Heart & Blood Cancer Brain Cancer
Type	Inhibitors
Purity	99.90
Formula	C13H17ClN2O2
Citations	[1]Nafiz Öncü Can, et al. Synthesis of New Hydrazone Derivatives for MAO Enzymes Inhibitory Activity. Molecules. 2017 Aug 20;22(8):1381. [2]Yun-feng Li, et al. Moclobemide up-regulates proliferation of hippocampal progenitor cells in chronically stressed mice. Acta Pharmacol Sin. 2004 Nov;25(11):1408-12.
Smiles	O=C(NCCN1CCOCC1)C2=CC=C(Cl)C=C2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Ro111163
Available
Product Description	Moclobemide (Ro111163) is a brain-penetrant and reversible monoamine oxidase (MAO-A) inhibitor with an IC50 of 6.061 μM for hMAO-A[1].Moclobemide up-regulates proliferation of hippocampal progenitor cells in chronically stressed mice.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
Molecular Weight	268.74
Clinical Information	Launched
Solubility	DMSO : 100 mg/mL (ultrasonic)
Isoform	MAO-A
Pathway	Neuronal Signaling
Manufacturers Product type	Reference compound

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HY-B0534-10mM-safety-datasheet.pdf