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Cloxacillin sodium monohydrate

Cloxacillin sodium monohydrate

€49.00

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Item no.	HY-B0466-500mg
Manufacturer	MedChem Express
CASRN	7081-44-9
Amount	500 mg
Category	Oncology Food Safety Antibiotics By Cell Type Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Purity	98.03
Formula	C19H19ClN3NaO6S
Citations	[1]Zhou H, et al. The combination of cloxacillin, thioridazine and tetracycline protects mice against Staphylococcus aureus peritonitis by inhibiting α-Hemolysin-induced MAPK/NF-κB/NLRP3 activation. Int J Biol Macromol. 2022 Feb 15;198:1-10. [2]Bergmann B, et al. Antibiotics with Interleukin-15 Inhibition Reduce Joint Inflammation and Bone Erosions but Not Cartilage Destruction in Staphylococcus aureus-Induced Arthritis. Infect Immun. 2018 Apr 23;86(5):e00960-17. [3]Lupiola-Gómez PA, et al. Group 1 beta-lactamases of Aeromonas caviae and their resistance to beta-lactam antibiotics. Can J Microbiol. 2003 Mar;49(3):207-15.
Smiles	O=C(C(C(C(C=CC=C1)=C1Cl)=NO2)=C2C)N[C@H]3[C@](SC(C)(C)[C@@H]4C(O[Na])=O)([H])N4C3=O.O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	7081-44-9
Available
Product Description	Cloxacillin sodium monohydrate is an orally active antibacterial agent and β-lactamase inhibitor with an IC50 of 0.04 µM. Cloxacillin sodium monohydrate can suppress the S. aureus-induced inflammatory response by inhibiting the activation of MAPKs, NF-кB and NLRP3-related proteins[1][2][3].
StorageTemperature	4°C (Powder, protect from light, stored under nitrogen)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
Molecular Weight	475.88
Clinical Information	Launched
Solubility	DMSO : 100 mg/mL (ultrasonic)\|H2O : 50 mg/mL (ultrasonic)
Isoform	Tetracycline
Pathway	Anti-infection
Manufacturers Product type	Reference compound

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HY-B0466-500mg-safety-datasheet.pdf