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Clomiphene citrate

Clomiphene citrate

Item no.	HY-B0463-10mM
Manufacturer	MedChem Express
CASRN	50-41-9
Amount	10 mM/1 mL
Category	Food Safety Drugs Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Purity	99.69
Formula	C32H36ClNO8
Citations	Biochem Biophys Res Commun. 2020 Feb 19;522(4):862-868. bioRxiv. 2020 May. J Pharmaceut Biomed. 2020, 113870. Patent. US11696914. [1]Jiann B P, et al. Effect of clomiphene on Ca2+ movement in human prostate cancer cells [J]. Life Sciences, 2002, 70(26): 3167-3178. [2]London S N, et al. Clomiphene citrate-induced perturbations during meiotic maturation and cytogenetic abnormalities in mouse oocytes in vivo and in vitro [J]. Fertility and sterility, 2000, 73(3): 620-626. [3]Akintoye O O, et al. Synergistic action of carvedilol and clomiphene in mitigating the behavioral phenotypes of letrozole-model of PCOS rats by modulating the NRF2/NFKB pathway [J]. Life Sciences, 2023, 324: 121737.
Smiles	Cl/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)/C3=CC=C(OCCN(CC)CC)C=C3.OC(CC(O)=O)(C(O)=O)CC(O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Clomifene citrate
Available
Product Description	Clomiphene citrate (Clomifene citrate) is an orally active estrogen-receptor modulator. Clomiphene citrate has anti-cancer actixity, induces perturbations during meiotic maturation and cytogenetic abnormalities and ameliorates in managing psychiatric and cognitive impairment[1][2][3].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Molecular Weight	598.08
Clinical Information	Launched
Solubility	DMSO : ≥ 50 mg/mL\|H2O : 1 mg/mL (ultrasonic)
Pathway	Vitamin D Related/Nuclear Receptor
Manufacturers Product type	Reference compound

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HY-B0463-10mM-safety-datasheet.pdf