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Azelastine hydrochloride

Azelastine hydrochloride

€49.00

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Item no.	HY-B0462-100mg
Manufacturer	MedChem Express
CASRN	79307-93-0
Amount	100 mg
Category	Food Safety Histamines Metabolism Diabetes Glucose Homeostasis Cell Biology Cell Stainings ECM Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Purity	99.93
Formula	C22H25Cl2N3O
Citations	[1]Craig La Force. Review of the pharmacology, clinical efficacy, and safety of azelastine hydrochloridel. Expert Rev Clin Immunol. 2005 Jul;1(2):191-201. [2]Mohamed M Elseweidy, et al. Azelastine a potent antihistamine agent, as hypolipidemic and modulator for aortic calcification in diabetic hyperlipidemic rats model. Arch Physiol Biochem. 2020 Jul 2;1-8. [3]Carlos D. Zappia, et al. Azelastine potentiates antiasthmatic dexamethasone effect on a murine asthma model. Pharmacol Res Perspect. 2019 Dec; 7(6): e00531. [4]Li Yang, et al. Identification of SARS-CoV-2 entry inhibitors among already approved drugs. Acta Pharmacol Sin. 2020 Oct 28 : 1–7. [5]Shao-Cheng Liu, et al. Effect of budesonide and azelastine on histamine signaling regulation in human nasal epithelial cells. Eur Arch Otorhinolaryngol. 2017 Feb;274(2):845-853.
Smiles	O=C1N(C2CCN(C)CCC2)N=C(CC3=CC=C(Cl)C=C3)C4=C1C=CC=C4.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	79307-93-0
Available
Product Description	Azelastine hydrochloridem, an antihistamine, is a potent and selective histamine 1 (H1) antagonist. Azelastine hydrochloride can be used for the research of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2[1][2][3][4].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
Molecular Weight	418.36
Clinical Information	Launched
Solubility	DMSO : 50 mg/mL (ultrasonic)\|H2O : 6.67 mg/mL (ultrasonic)
Isoform	H1 Receptor
Pathway	Anti-infection; GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-B0462-100mg-safety-datasheet.pdf