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Methacycline hydrochloride

Methacycline hydrochloride

€65.00

Excl. VAT

Item no.	HY-B0449-100mg
Manufacturer	MedChem Express
CASRN	3963-95-9
Amount	100 mg
Category	Oncology Food Safety Antibiotics Neuroscience Neural Lineage Markers By Cell Type Blastoma Carcinoma Cell Biology Cell Status Proliferation Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer
Type	Inhibitors
Purity	99.71
Formula	C22H23ClN2O8
Citations	[1]Ying Xi, et al. Inhibition of epithelial-to-mesenchymal transition and pulmonary fibrosis by methacycline. Am J Respir Cell Mol Biol. 2014 Jan;50(1):51-60.
Smiles	O[C@@](C(O)=C(C(C1=C2C=CC=C1O)=O)[C@](C2=C)([H])[C@@H]3O)(C(C(C(N)=O)=C4O)=O)[C@]3([H])[C@@H]4N(C)C.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	3963-95-9
Available
Product Description	Methacycline hydrochloride is a tetracycline antibiotic and can inhibits bacterial protein synthesis. Methacycline hydrochloride is a potent epithelial-mesenchymal transition (EMT) inhibitor. Methacycline hydrochloride blocks EMT in vitro and fibrogenesis in vivo without directly affecting TGF-β1 Smad signaling. Methacycline hydrochloride is an antimicrobial and has the potential for pulmonary fibrosis[1].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
Molecular Weight	478.88
Clinical Information	Launched
Solubility	DMSO : 50 mg/mL (ultrasonic)\|H2O : 6.67 mg/mL (ultrasonic)
Isoform	Tetracycline
Pathway	Anti-infection
Manufacturers Product type	Reference compound

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HY-B0449-100mg-safety-datasheet.pdf