Comparison

Captopril European Partner

€65.00
Excl. VAT
Item no. HY-B0368-100mg
Manufacturer MedChem Express
CASRN 62571-86-2
Amount 100 mg
Category
Type Inhibitors
Purity 99.85
Formula C9H15NO3S
Citations [1]Esmaeili S, et al. Captopril/enalapril inhibit promiscuous esterase activity of carbonic anhydrase at micromolar concentrations: An in vitro study. Chem Biol Interact. 2017;265:24-35.
[2]Li N, et al. Simplified captopril analogues as NDM-1 inhibitors. Bioorg Med Chem Lett. 2014;24(1):386-389.
[3]Afrin S, et al. Eritadenine from Edible Mushrooms Inhibits Activity of Angiotensin Converting Enzyme in Vitro. J Agric Food Chem. 2016;64(11):2263-2268.
[4]Tzakos, A.G., et al., The molecular basis for the selection of captopril cis and trans conformations by angiotensin I converting enzyme. Bioorg Med Chem Lett, 2006. 16(19): p. 5084-7.
[5]Song, J.C. and C.M. White, Clinical pharmacokinetics and selective pharmacodynamics of new angiotensin converting enzyme inhibitors: an update. Clin Pharmacokinet, 2002. 41(3): p. 207-24.
Smiles O=C(O)[C@H]1N(C([C@H](C)CS)=O)CCC1
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias SQ 14225
Available
Product Description
Captopril (SQ 14225), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM) and has been widely used for research of hypertension and congestive heart failure. Captopril is also a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC50 of 7.9 μM[1][2][3].
StorageTemperature
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping
Room Temperature
Manufacturers Applications
Neuroscience-Neuromodulation
Molecular Weight
217.29
Clinical Information
Launched
Solubility
DMSO : ≥ 50 mg/mL|H2O : ≥ 50 mg/mL
Pathway
Metabolic Enzyme/Protease
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
Listprice: €65.00
Price: €65.00
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