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Sulfapyridine

Sulfapyridine

Item no.	HY-B0212-1g
Manufacturer	MedChem Express
CASRN	144-83-2
Amount	1 g
Category	Oncology Food Safety Antibiotics Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer Testicular & Prostate Cancer
Type	Inhibitors
Purity	99.85
Formula	C11H11N3O2S
Citations	[1]Kazuki Omoteyama, et al. Effects of salazosulfapyridine on the profile of cell surface proteins, revealed by biotinylation of cell surface proteins and 2-dimentional electrophoresis. Biochim Biophys Acta Proteins Proteom. 2019 Jan;1867(1):47-56. [2]J J Andreasen, et al. In vitro susceptibility of diarrhoea producing gram negative enteric bacteria to sulfasalazine, 5-aminosalicylic acid, sulfapyridine and four quinolones. Brief report. APMIS. 1988 Jun;96(6):568-70. [3]Y L Hong, et al. Inhibition of recombinant Pneumocystis carinii dihydropteroate synthetase by sulfa drugs. Antimicrob Agents Chemother. 1995 Aug;39(8):1756-63. [4]H M Kim, et al. Inhibitory effect of mast cell-mediated immediate-type allergic reactions by sulfapyridine. Immunopharmacol Immunotoxicol. 2000 May;22(2):253-66.
Smiles	O=S(C1=CC=C(N)C=C1)(NC2=NC=CC=C2)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	144-83-2
Available
Product Description	Sulfapyridine, a major metabolite of Sulfasalazine, is a sulfonamide antibiotic agent. Sulfapyridine inhibits recombinant P. carinii dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM. Sulfapyridine has antibacterial, anti-inflammatory and anti-rheumatic activities[1][2][3].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
Molecular Weight	249.29
Clinical Information	Launched
Solubility	DMSO : 60 mg/mL (ultrasonic)\|H2O : < 0.1 mg/mL
Pathway	Anti-infection
Manufacturers Product type	Reference compound

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HY-B0212-1g-safety-datasheet.pdf