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Folinic acid calcium salt pentahydrate

Folinic acid calcium salt pentahydrate

€49.00

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Item no.	HY-B0080-100mg
Manufacturer	MedChem Express
CASRN	6035-45-6
Amount	100 mg
Category	Food Safety Vitamines Neuroscience Neural Development Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Purity	98.0
Formula	C20H31CaN7O12
Citations	J Mol Med (Berl). 2019 Aug;97(8):1183-1193. Appl Microbiol Biotechnol. 2024 Dec;108(1):1-15. bioRxiv. 2023 Feb 28. JAMA Oncol. 2022 Jan 1;8(1):e215445. Mol Oncol. 2020 Nov;14(11):2894-2919. NPJ Precis Oncol. 2023 Dec 8;7(1):128. Virology. 2023 Jun 21. J Mol Med (Berl). 2019 Aug;97(8):1183-1193. [1]Keshava C, et al. Inhibition of methotrexate-induced chromosomal damage by folinic acid in V79 cells. Mutat Res. 1998 Feb 2;397(2):221-8. [2] Iqbal MP, et al. Effect of methotrexate and folinic acid on skeletal growth in mice. Acta Paediatr. 2003 Dec;92(12):1438-44.
Smiles	O=CN1C(C2=O)=C(NC(N)=N2)NCC1CNC3=CC=C(C(N[C@H](C([O-])=O)CCC([O-])=O)=O)C=C3.O.O.O.O.[Ca+2].O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Leucovorin (calcium salt pentahydrate)
Available
Product Description	Folinic acid calcium salt pentahydrate (Leucovorin calcium salt pentahydrate) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity[1].
StorageTemperature	4°C (Powder, sealed storage, away from moisture and light)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
Molecular Weight	601.58
Clinical Information	Launched
Solubility	DMSO : 1 mg/mL (ultrasonic; warming; heat to 80°C)\|H2O : 10 mg/mL (ultrasonic)
Isoform	Human Endogenous Metabolite
Pathway	Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-B0080-100mg-safety-datasheet.pdf