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Lurasidone Hydrochloride

Lurasidone Hydrochloride

€71.00

Excl. VAT

Item no.	HY-B0032-10mg
Manufacturer	MedChem Express
CASRN	367514-88-3
Amount	10 mg
Category	Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Inhibitors & Compound Libraries Small Molecules Neuronal Cell Markers
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	99.96
Formula	C28H37ClN4O2S
Citations	Marmara Pharm J. 2017;21 (4): 931-937. Marmara Pharm J. 2017;21 (4): 931-937. Marmara Pharm J. 2017;21 (4): 931-937. Nature. 2023 Dec;624(7992):672-681. [1]Ishibashi T, et al. Pharmacological profile of lurasidone, a novel antipsychotic agent with potent 5-hydroxytryptamine 7 (5-HT7) and 5-HT1A receptor activity. J Pharmacol Exp Ther. 2010 Jul;334(1):171-81. [2]Sakine Atila Karaca, et al. Development of a validated high-performance liquid chromatographic method for the determination of Lurasidone in pharmaceuticals. Marmara Pharm J. 2017;21 (4): 931-937.
Smiles	O=C([C@H]([C@H]1CC[C@@H]2C1)[C@H]2C3=O)N3C[C@@H]4CCCC[C@H]4CN(CC5)CCN5C6=NSC7=CC=CC=C76.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	SM-13496 (Hydrochloride)
Available
Product Description	Lurasidone (Hydrochloride) (SM-13496 (Hydrochloride)) is an antagonist of both dopamine D2 and 5-HT7 with IC50s of 1.68 and 0.495 nM, respectively. Lurasidone (Hydrochloride) (SM-13496 (Hydrochloride)) is also a partial agonist of 5-HT1A receptor with an IC50 of 6.75 nM.
StorageTemperature	4°C (Powder, sealed storage, away from moisture and light)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
Molecular Weight	529.14
Clinical Information	Launched
Solubility	DMSO : 6.67 mg/mL (ultrasonic; warming; adjust pH to 3 with HCl; heat to)\|Ethanol : 2 mg/mL (ultrasonic)\|H2O : 1 mg/mL (ultrasonic; warming; heat to 80°C)
Isoform	5-HT1 Receptor; 5-HT7 Receptor; D2 Receptor
Pathway	GPCR/G Protein; Neuronal Signaling
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-B0032-10mg-safety-datasheet.pdf