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Cinacalcet hydrochloride

Cinacalcet hydrochloride

€54.00

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Item no.	HY-70037A-10mg
Manufacturer	MedChem Express
CASRN	364782-34-3
Amount	10 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Thyroid Cancer
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	99.99
Formula	C22H23ClF3N
Citations	iScience. 2023 Mar. Patent. US20230147129A1. Acta Physiol. 2023 Jan 6;e13926. Calcif Tissue Int. 2023 Feb 8. Cell Biol Toxicol. 2022 May 30. Gen Comp Endocrinol. 2018 Oct 1;267:1-8. J Agric Food Chem. 2021 Nov 8. J Biol Chem. 2016 Oct 28;291(44):23126-23135. J Food Sci. 2018 Sep;83(9):2394-2401. J Med Chem. 2015 Apr 9;58(7):2958-66. Oxid Med Cell Longev. 2017;2017:3869561. Oxid Med Cell Longev. 2021 Jan 12;2021:3010548. [1]Colloton M, et al. Cinacalcet HCl attenuates parathyroid hyperplasia in a rat model of secondary hyperparathyroidism. Kidney Int. 2005 Feb;67(2):467-76. [2]D.A. Bushinsky, et al. Effect of cinacalcet on urine calcium excretion and supersaturation in genetic hypercalciuric stone-forming rats. Kidney Int. 2006 May;69(9):1586-92.
Smiles	FC(F)(C1=CC(CCCN[C@@H](C2=C3C=CC=CC3=CC=C2)C)=CC=C1)F.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	AMG-073 (hydrochloride)
Available
Product Description	Cinacalcet hydrochloride (AMG-073 hydrochloride) is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease treatment.
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
Molecular Weight	393.87
Clinical Information	Launched
Solubility	DMSO : ≥ 50 mg/mL\|H2O : 1 mg/mL (ultrasonic; warming; heat to 60°C)
Pathway	GPCR/G Protein; Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-70037A-10mg-safety-datasheet.pdf