MP-A08

€34.00

Excl. VAT

Item no.	HY-19794-1mg
Manufacturer	MedChem Express
CASRN	219832-49-2
Amount	1 mg
Category	Oncology Metabolism Cholesterol & Lipid Metabolism Enzymes Other Fatty Acid Enzymes Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer
Type	Inhibitors
Specific against	other
Purity	98.0
Formula	C27H25N3O4S2
Citations	[1]Pitman MR et al. A selective ATP-competitive sphingosine kinase inhibitor demonstrates anti-cancer properties. Oncotarget, 2015 Mar 30, 6(9):7065-83. [2]Dimasi DP et al. Examining the Role of Sphingosine Kinase-2 in the Regulation of Endothelial Cell Barrier Integrity. Microcirculation, 2016 Apr, 23(3):248-65.
Smiles	O=S(C1=CC=C(C)C=C1)(NC2=CC=CC=C2/C=N/C3=CC=CC=C3NS(=O)(C4=CC=C(C)C=C4)=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	219832-49-2
Available
Product Description	MP-A08 is a highly selective ATP competitive sphingosine kinase (SPHK1) inhibitor that targets both SphK1 and SphK2 with Ki values of 6.9 ± 0.8 μM and 27 ± 3 μM, respectively.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
Molecular Weight	519.64
Clinical Information	No Development Reported
Solubility	DMSO : ≥ 50 mg/mL
Isoform	SphK1
Pathway	Immunology/Inflammation
Manufacturers Product type	Reference compound

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HY-19794-1mg-safety-datasheet.pdf