JW74

€826.00

Excl. VAT

Item no.	HY-19739-100mg
Manufacturer	MedChem Express
CASRN	863405-60-1
Amount	100 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Bone Cancer
Type	Inhibitors
Specific against	other
Purity	98.32
Formula	C24H20N6O2S
Citations	[1]Waaler J, et al. Novel synthetic antagonists of canonical Wnt signaling inhibit colorectal cancer cell growth. Cancer Res. 2011 Jan 1;71(1):197-205. [2]Stratford EW, et al. The tankyrase-specific inhibitor JW74 affects cell cycle progression and induces apoptosis and differentiation in osteosarcoma cell lines. Cancer Med. 2014 Feb;3(1):36-46.
Smiles	CC1=CC=C(C2=NOC(CSC3=NN=C(C4=CC=NC=C4)N3C5=CC=C(OC)C=C5)=N2)C=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	863405-60-1
Available
Product Description	JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling with an IC50 of 420 nM.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
Molecular Weight	456.52
Clinical Information	No Development Reported
Solubility	DMSO : ≥ 50 mg/mL
Pathway	Stem Cell/Wnt
Manufacturers Product type	Reference compound

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HY-19739-100mg-safety-datasheet.pdf