« Back
Home /
BEC hydrochloride

BEC hydrochloride

€119.00

Excl. VAT

Item no.	HY-19548A-10mM
Manufacturer	MedChem Express
CASRN	222638-67-7
Amount	10 mM/1 mL
Category	Oncology Neuroscience Molecular Targets for Neuroscience Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer Skin Cancer Hepatic Cancer
Type	Inhibitors
Specific against	other
Purity	98.0
Formula	C5H13BClNO4S
Citations	[1]Colleluori DM, et al. Classical and slow-binding inhibitors of human type II arginase. Biochemistry. 2001 Aug 7;40(31):9356-62. [2]Kim NN, et al. Probing erectile function: S-(2-boronoethyl)-L-cysteine binds to arginase as a transition state analogue and enhances smooth muscle relaxation in human penile corpus cavernosum. Biochemistry. 2001 Mar 6;40(9):2678-88. [3]Ckless K, et al. Inhibition of arginase activity enhances inflammation in mice with allergic airway disease, in association with increases in protein S-nitrosylation and tyrosine nitration. J Immunol. 2008 Sep 15;181(6):4255-64.
Smiles	N[C@@H](CSCCB(O)O)C(O)=O.[H]Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	222638-67-7
Available
Product Description	BEC hydrochloride is a slow-binding and competitive Arginase II inhibitor with Ki of 0.31 μM and 30 nM at pH 7.5 and pH 9.5, respectively[1].
StorageTemperature	4°C (Powder, stored under nitrogen)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
Molecular Weight	229.49
Clinical Information	No Development Reported
Solubility	DMSO : 50 mg/mL (ultrasonic)\|H2O : 50 mg/mL (ultrasonic)
Pathway	Immunology/Inflammation; Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

HY-19548A-10mM-safety-datasheet.pdf