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Endoxifen hydrochloride

Endoxifen hydrochloride

€275.00

Excl. VAT

Item no.	HY-18719B-50mg
Manufacturer	MedChem Express
CASRN	1197194-41-4
Amount	50 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Breast Cancer
Type	Inhibitors
Specific against	other
Purity	98.20
Formula	C25H28ClNO2
Citations	[1]Goetz MP, et al. Tamoxifen, endoxifen, and CYP2D6: the rules for evaluating a predictive factor. Oncology (Williston Park). 2009 Dec;23(14):1233-4, 1236. [2]Wu X, et al. The tamoxifen metabolite, Endoxifen, is a potent antiestrogen that targets estrogen receptor alpha fordegradation in breast cancer cells. Cancer Res. 2009 Mar 1;69(5):1722-7.
Smiles	OC1=CC=C(/C(C2=CC=C(OCCNC)C=C2)=C(C3=CC=CC=C3)\CC)C=C1.[H]Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1197194-41-4
Available
Product Description	Endoxifen hydrochloride is a key active metabolite of Tamoxifen (TAM) with higher affinity and specificity to estrogen receptor that also inhibits aromatase activity. Endoxifen hydrochloride has the potential for breast cancer study[1][2].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
Molecular Weight	409.95
Clinical Information	Phase 3
Solubility	DMSO : ≥ 35 mg/mL\|H2O : 1 mg/mL (ultrasonic; warming; heat to 80°C)
Isoform	Aromatase/CYP19A1
Pathway	Anti-infection; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Manufacturers Product type	Reference compound

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HY-18719B-50mg-safety-datasheet.pdf