Comparison

Enasidenib European Partner

€54.00
Excl. VAT
Item no. HY-18690-10mM
Manufacturer MedChem Express
CASRN 1446502-11-9
Amount 10 mM/1 mL
Category
Type Inhibitors
Clone N/A
Specific against other
Purity 99.97
Formula C19H17F6N7O
Citations [1]Exploring the Pathway: IDH Mutations and Metabolic Dysregulation in Cancer Cells: A Novel Therapeutic Target. MAY 29, 2015
[2]Alan H. Shih, et al. AG-221, a Small Molecule Mutant IDH2 Inhibitor, Remodels the Epigenetic State of IDH2-Mutant Cells and Induces Alterations in Self-Renewal/Differentiation in IDH2-Mutant AML Model in Vivo. Blood 2014 124:437.
Smiles CC(O)(C)CNC1=NC(C2=NC(C(F)(F)F)=CC=C2)=NC(NC3=CC(C(F)(F)F)=NC=C3)=N1
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias AG-221
Available
Product Description
Enasidenib is an oral, potent, reversible, selective inhibitor of the IDH2 mutant enzymes, with IC50s of 100 and 400 nM against IDH2R140Q and IDH2R172K, respectively.
StorageTemperature
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping
Room Temperature
Manufacturers Applications
Cancer-programmed cell death
Molecular Weight
473.38
Clinical Information
Launched
Solubility
DMSO : 50 mg/mL (ultrasonic)
Isoform
IDH2
Pathway
Metabolic Enzyme/Protease
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mM/1 mL
Available: In stock
Listprice: €54.00
Price: €54.00
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