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G-418 disulfate

G-418 disulfate

€189.00

Excl. VAT

Item no.	HY-17561-5g
Manufacturer	MedChem Express
CASRN	108321-42-2
Amount	5 g
Category	Food Safety Antibiotics Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.26
Formula	C20H44N4O18S2
Citations	Am J Cancer Res. 2021 May 15;11(5):2062-2080. Cancer Commun (Lond). 2022 Nov 9. Cancer Res. 2023 Feb 6;CAN-22-3169. Cell Death Differ. 2020 Jun;27(6):1981-1997. Cell Death Dis. 2020 Jun 4;11(6):420. Cell Death Dis. 2019 May 28;10(6):413. Cell Rep. 2020 Oct 20;33(3):108287. Cell Rep. 2021 Mar 30;34(13):108906. Cell Rep. 2021 Sep 21;36(12):109739. Cell Rep. 2022 Oct 25;41(4):111561. Emerg Microbes Infect. 2023 Sep 19;2261556. Hum Cell. 2022 Jul 6. J Agric Food Chem. 2022 Apr 6;70(13):3989-3999. J Biol Chem. 2023 Mar 17;104621. J Cell Mol Med. 2023 Mar 13. J Genet Genomics. 2021 Mar 30. Med Oncol. 2021 Nov 10;39(1):10. Mol Cell. 2023 Nov 20:S1097-2765(23)00914-0. Nature. 2023 Jun;618(7966):862-870. Oxid Med Cell Longev. 2022 Jan 28;2022:8168988. Research Square Preprint. 2020 Jun. Research Square Preprint. 2021 Nov. Research Square Print. 2023 Feb 21. Theranostics. 2022 Jan 1;12(3):1187-1203. Transl Cancer Res. 2023 Jan 23; 12(1):150-162. Acta Pharmacol Sin. 2023 May 16. FASEB J. 2023 Nov;37(11):e23195. Research Square Preprint. 2023 Jul 11. [1]Giordano-Santini R, et al. An antibiotic selection marker for nematode transgenesis. Nat Methods. 2010;7(9):721-723. [2]Volarevic M, et al. A novel G418 conjugate results in targeted selection of genetically protected hepatocytes without bystander toxicity. Bioconjug Chem. 2007;18(6):1965-1971. [3]Kwon KM, et al. Disialyl GD2 ganglioside suppresses ICAM-1-mediated invasiveness in human breast cancer MDA-MB231 cells. Int J Biol Sci. 2017;13(3):265-275. Published 2017 Feb 12. [4]Davies J, et al. A new selective agent for eukaryotic cloning vectors. Am J Trop Med Hyg. 1980;29(5 Suppl):1089-1092.
Smiles	O=S(O)(O)=O.O[C@@H]([C@@H]1O[C@@]([C@@H]([C@@H](O)[C@@H]2O)N)([H])O[C@]2([H])[C@H](O)C)[C@H]([C@@H](C[C@@H]1N)N)O[C@](OC[C@](C)(O)[C@@H]3NC)([H])[C@@H]3O.O=S(O)(O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Geneticin sulfate; Antibiotic G-418 sulfate
Available
Product Description	G-418 disulfate (Geneticin sulfate), is an aminoglycoside antibiotic, inhibits protein synthesis in eukaryotes and prokaryotes. G-418 disulfate is commonly used as a selective agent for eukaryotic cells[1].
StorageTemperature	4°C (Powder, stored under nitrogen, away from moisture)
Shipping	Room Temperature
Molecular Weight	692.71
Clinical Information	No Development Reported
Solubility	H2O : 125 mg/mL (ultrasonic)
Isoform	Aminoglycoside
Pathway	Anti-infection
Manufacturers Product type	Natural Products

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-17561-5g-safety-datasheet.pdf