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Onatasertib

Onatasertib

€142.00

Excl. VAT

Item no.	HY-16956-5mg
Manufacturer	MedChem Express
CASRN	1228013-30-6
Amount	5 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer Breast Cancer Hepatic Cancer
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	97.0
Formula	C21H27N5O3
Citations	[1]Mortensen DS, et al. CC-223, a Potent and Selective Inhibitor of mTOR Kinase: In Vitro and In Vivo Characterization. Mol Cancer Ther. 2015 Jun;14(6):1295-305.
Smiles	O=C1CNC2=NC=C(C3=CC=C(C(C)(O)C)N=C3)N=C2N1[C@H]4CC[C@H](OC)CC4
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	CC-223; ATG-008
Available
Product Description	Onatasertib (CC-223) is a potent, selective, and orally bioavailable inhibitor of mTOR kinase, with an IC50 value for mTOR kinase of 16 nM. Onatasertib inhibits both mTORC1 and mTORC2.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
Molecular Weight	397.47
Clinical Information	Phase 2
Solubility	DMSO : ≥ 27 mg/mL
Isoform	mTOR; mTORC1; mTORC2
Pathway	Apoptosis; PI3K/Akt/mTOR
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-16956-5mg-safety-datasheet.pdf