« Back
Home /
JNJ 303

JNJ 303

Item no.	HY-16953-10mg
Manufacturer	MedChem Express
CASRN	878489-28-2
Amount	10 mg
Category	Cardiovascular Research Ischemia & Reperfusion Injury Hypertension Inhibitors & Compound Libraries Small Molecules Arrhythmias
Type	Inhibitors
Purity	99.60
Formula	C21H29ClN2O4S
Citations	[1]Julie Albrecht, et al. The effect of the KV7/KCNE 1 inhibitor JNJ 303 on heart slices and the L-type calcium channel of cardiac cells. [2]Zhaohuan Huang, et al. Glucose-sensing glucagon-like peptide-1 receptor neurons in the dorsomedial hypothalamus regulate glucose metabolism. Sci Adv. 2022 Jun 10;8(23):eabn5345.
Smiles	ClC1=CC=C(OC(C)(C)C(N[C@@H]([C@@H](C2)C3)[C@@H]4C[C@H]2C[C@@]3(NS(=O)(C)=O)C4)=O)C=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	878489-28-2
Available
Product Description	JNJ-303 is a specific delayed rectifier Kv blocker. JNJ 303 can potent block IKs with an IC50 value of 64 nM. JNJ-303 can be used for the research of diabetes, obesity and central nervous system[1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
Molecular Weight	440.98
Clinical Information	No Development Reported
Solubility	DMSO : 62.5 mg/mL (ultrasonic)
Pathway	Membrane Transporter/Ion Channel
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

HY-16953-10mg-safety-datasheet.pdf