« Back
Home /
Kartogenin

Kartogenin

€60.00

Excl. VAT

Item no.	HY-16268-10mM
Manufacturer	MedChem Express
CASRN	4727-31-5
Amount	10 mM/1 mL
Category	Oncology Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Inhibitors & Compound Libraries Small Molecules By Organ Colorectal Cancer Head & Neck Cancer Gastric Cancer
Type	Inhibitors
Purity	98.30
Formula	C20H15NO3
Citations	[1]Johnson K, et, al. A stem cell-based approach to cartilage repair. Science. 2012 May 11;336(6082):717-21. [2]Liu F, et, al. A novel kartogenin-platelet-rich plasma gel enhances chondrogenesis of bone marrow mesenchymal stem cells in vitro and promotes wounded meniscus healing in vivo. Stem Cell Res Ther. 2019 Jul 8;10(1):201.
Smiles	O=C(O)C1=CC=CC=C1C(NC2=CC=C(C3=CC=CC=C3)C=C2)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	KGN
Available
Product Description	Kartogenin (KGN) is an inducer of differentiation of human mesenchymal stem cells into chondrocytes, with an EC50 of 100 nM. Kartogenin binds filamin A, disrupts its interaction with the transcription factor core-binding factor β subunit (CBFβ), and induces chondrogenesis by regulating the CBFβ-RUNX1 transcriptional program. Kartogenin can be used for the research of osteoarthritis (OA)[1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Molecular Weight	317.34
Clinical Information	No Development Reported
Solubility	DMSO : ≥ 42 mg/mL\|H2O : 1 mg/mL (ultrasonic; warming; heat to 60°C)
Pathway	Stem Cell/Wnt; TGF-beta/Smad
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

HY-16268-10mM-safety-datasheet.pdf