Comparison

BQ-788 sodium salt European Partner

€177.00
Excl. VAT
Item no. HY-15894-1mg
Manufacturer MedChem Express
CASRN 156161-89-6
Amount 1 mg
Category
Type Inhibitors
Purity 98.56
Formula C34H50N5NaO7
Citations BMC Cancer. 2018 Feb 6;18(1):154.
Environ Sci Pollut Res Int. 2018 May;25(15):14713-14725.
PLoS Pathog. 2020 Oct 19;16(10):e1008947.
Cells. 2021, 10(11), 3072.
Environ Pollut. 2016 Feb;209:11-20.
Environ Pollut. 2016 Nov;218:487-496.
Neurotherapeutics. 2021 Oct 18.
Toxicol Sci. 2016 Jan;149(1):213-26.
[1]Fattori V, et al. Differential regulation of oxidative stress and cytokine production by endothelin ETA and ETB receptors in superoxide anion-induced inflammation and pain in mice. J Drug Target. 2016 Oct 5:1-27
[2]Sargent CA, et al. Effect of endothelin antagonists with or without BQ 788 on ET-1 responses in pithed rats. J Cardiovasc Pharmacol. 1995;26 Suppl 3:S216-8.
[3]Okada M, et al. BQ-788, a selective endothelin ET(B) receptor antagonist. Cardiovasc Drug Rev. 2002 Winter;20(1):53-66.
Smiles CCCC[C@H](C(O[Na])=O)NC([C@@H](CC1=CN(C(OC)=O)C2=CC=CC=C12)NC([C@H](CC(C)(C)C)NC(N3[C@H](C)CCC[C@@H]3C)=O)=O)=O
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 156161-89-6
Available
Product Description
BQ-788 sodium salt is a potent and selective ETB receptor antagonist, inhibiting ET-1 binding to ETB receptors with an IC50 of 1.2 nM in human Girrardi heart cells[1].
StorageTemperature
-20°C (Powder, protect from light, stored under nitrogen)
Shipping
Blue Ice
Manufacturers Applications
COVID-19-immunoregulation
Molecular Weight
663.78
Clinical Information
Phase 1
Solubility
DMSO : ≥ 43 mg/mL|H2O : 20 mg/mL (ultrasonic)
Isoform
ETB
Pathway
GPCR/G Protein
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mg
Available: In stock
Listprice: €177.00
Price: €177.00
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