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5-Aminosalicylic Acid

5-Aminosalicylic Acid

€60.00

Excl. VAT

Item no.	HY-15027-10mM
Manufacturer	MedChem Express
CASRN	89-57-6
Amount	10 mM/1 mL
Category	Metabolism Cholesterol & Lipid Metabolism Enzymes Other Fatty Acid Enzymes Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	99.91
Formula	C7H7NO3
Citations	[1]Rousseaux C, et al. The 5-aminosalicylic acid antineoplastic effect in the intestine is mediated by PPARγ. Carcinogenesis. 2013 Nov;34(11):2580-6. [2]Dammann K, et al. PAK1 modulates a PPARγ/NF-κB cascade in intestinal inflammation. Biochim Biophys Acta. 2015 Oct;1853(10 Pt A):2349-60. [3]Fang HM, et al. 5-aminosalicylic acid in combination with Nimesulide inhibits proliferation of colon carcinoma cells in vitro. World J Gastroenterol. 2007 May 28;13(20):2872-7.
Smiles	OC1=C(C(O)=O)C=C(N)C=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Mesalamine; 5-ASA; Mesalazine
Available
Product Description	5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB.
StorageTemperature	4°C (Powder, protect from light, stored under nitrogen)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-anti-virus
Molecular Weight	153.14
Clinical Information	Launched
Solubility	DMSO : 66.67 mg/mL (ultrasonic; warming; heat to 60°C)\|H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Isoform	PAK1; PPARγ; RelA/p65
Pathway	Cell Cycle/DNA Damage; Cytoskeleton; Metabolic Enzyme/Protease; NF-κB; Vitamin D Related/Nuclear Receptor
Manufacturers Product type	Natural Products

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-15027-10mM-safety-datasheet.pdf