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Palifosfamide

Palifosfamide

€344.00

Excl. VAT

Item no.	HY-14798-10mg
Manufacturer	MedChem Express
CASRN	31645-39-3
Amount	10 mg
Category	Food Safety Allergenes Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Purity	97.0
Formula	C4H11Cl2N2O2P
Citations	[1]Hingorani P, et al. Preclinical activity of palifosfamide lysine (ZIO-201) in pediatric sarcomas including oxazaphosphorine-resistant osteosarcoma. Cancer Chemother Pharmacol. 2009 Sep;64(4):733-40. [2]Jones B, et al. Anticancer activity of stabilized palifosfamide in vivo: schedule effects, oral bioavailability, and enhanced activity with docetaxel and doxorubicin. Anticancer Drugs. 2012 Feb;23(2):173-84.
Smiles	O=P(NCCCl)(NCCCl)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Isophosphoramide mustard; IPM; ZIO-201
Available
Product Description	Palifosfamide is a novel DNA alkylator and the active metabolite of ifosfamide, with antitumor activity.
StorageTemperature	-20°C (Powder, protect from light, stored under nitrogen)
Shipping	Blue Ice
Manufacturers Applications	Cancer-programmed cell death
Molecular Weight	221.02
Clinical Information	Phase 2
Solubility	DMSO : 40 mg/mL (ultrasonic)\|H2O : 14.29 mg/mL (ultrasonic)
Pathway	Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-14798-10mg-safety-datasheet.pdf