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Vosilasarm

Vosilasarm

€65.00

Excl. VAT

Item no.	HY-14383-5mg
Manufacturer	MedChem Express
CASRN	1182367-47-0
Amount	5 mg
Category	Oncology Food Safety Hormones Inhibitors & Compound Libraries Small Molecules By Organ Breast Cancer Testicular & Prostate Cancer
Type	Inhibitors
Purity	99.45
Formula	C20H16ClN5O2
Citations	[1]Miller CP, et al. Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140. ACS Med Chem Lett. 2010 Dec 2;2(2):124-129. [2]Jayaraman A, et al. Selective androgen receptor modulator RAD140 is neuroprotective in cultured neurons and kainate-lesioned male rats. Endocrinology. 2014 Apr;155(4):1398-1406.
Smiles	ClC1=C(C)C(N[C@]([H])([C@@]([H])(O)C)C2=NN=C(O2)C3=CC=C(C#N)C=C3)=CC=C1C#N
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	RAD140
Available
Product Description	Vosilasarm (RAD140) is a potent, orally active, nonsteroidal selective androgen receptor modulator (SARM) with a Ki of 7 nM. Vosilasarm shows good selectivity over other steroid hormone nuclear receptors[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
Molecular Weight	393.83
Clinical Information	Phase 1
Solubility	DMSO : ≥ 100 mg/mL
Pathway	Vitamin D Related/Nuclear Receptor
Manufacturers Product type	Reference compound

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HY-14383-5mg-safety-datasheet.pdf